Professor, Department of Pharmacology
University of Colorado School of Medicine
Dr. Tanya Kutateladze is a Professor in the Department of Pharmacology of the University of Colorado School of Medicine. Her research interests include studying epigenetic mechanisms, posttranslational histone modifications, and the role of epigenetic misregulations in human diseases, cancer in particular. The Kutateladze’s group has substantially contributed to deciphering the epigenetic language through characterizing structures and functions of chromatin-binding and chromatin-remodeling proteins. Her laboratory applies latest breakthroughs in high field NMR spectroscopy and X-ray crystallography to unveil the atomic-resolution structures and mechanistic aspects of chromatin-interacting proteins involved in transcriptional regulation and DNA damage repair. Among her many achievements, Dr. Kutateladze is credited with elucidating the molecular mechanisms of the methyllysine and acyllysine recognition by a large number of epigenetic readers, including PHD, Tudor, YEATS, ZZ, bromodomain, CW and PZP. Dr. Kutateladze has published over 140 papers in the field of epigenetics and cancer, with many in leading journals.